Hemoglobin α / eNOS Coupling at Myoendothelial Junctions is Required for Nitric Oxide Scavenging During Vasoconstriction

OBJECTIVE: Hb α and eNOS form a macromolecular complex at myoendothelial junctions; the functional role of this interaction remains undefined. To test if coupling of eNOS and Hb α regulates NO signaling, vascular reactivity and blood pressure using a mimetic peptide of Hb α to disrupt this interacti...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Straub, Adam C., Butcher, Joshua T., Billaud, Marie, Mutchler, Stephanie M., Artamonov, Mykhaylo V., Nguyen, Anh T., Johnson, Tyler, Best, Angela K., Miller, Megan P., Palmer, Lisa A., Columbus, Linda, Somlyo, Avril V., Le, Thu H., Isakson, Brant E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239174/
https://ncbi.nlm.nih.gov/pubmed/25278292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.303974
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