Islet-1 Is Essential for Pancreatic β-Cell Function

Islet-1 (Isl-1) is essential for the survival and ensuing differentiation of pancreatic endocrine progenitors. Isl-1 remains expressed in all adult pancreatic endocrine lineages; however, its specific function in the postnatal pancreas is unclear. Here we determine whether Isl-1 plays a distinct rol...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Ediger, Benjamin N., Du, Aiping, Liu, Jingxuan, Hunter, Chad S., Walp, Erik R., Schug, Jonathan, Kaestner, Klaus H., Stein, Roland, Stoffers, Doris A., May, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237994/
https://ncbi.nlm.nih.gov/pubmed/25028525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0096
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