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Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

OBJECTIVE: The generation of mature cell types during pancreatic development depends on the expression of many regulatory and signaling proteins. In this study, we tested the hypothesis that the transcriptional regulator Islet-1 (Isl-1), whose expression is first detected in the mesenchyme and epith...

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Detalhes bibliográficos
Main Authors: Du, Aiping, Hunter, Chad S., Murray, Johanna, Noble, Daniel, Cai, Chen-Leng, Evans, Sylvia M., Stein, Roland, May, Catherine Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731519/
https://ncbi.nlm.nih.gov/pubmed/19502415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0987
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