Islet-1 Regulates Arx Transcription during Pancreatic Islet α-Cell Development

Aristaless related homeodomain protein (Arx) specifies the formation of the pancreatic islet α-cell during development. This cell type produces glucagon, a major counteracting hormone to insulin in regulating glucose homeostasis in adults. However, little is known about the factors that regulate Arx...

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Hlavní autoři: Liu, Jingxuan, Hunter, Chad S., Du, Aiping, Ediger, Benjamin, Walp, Erik, Murray, Johanna, Stein, Roland, May, Catherine Lee
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083195/
https://ncbi.nlm.nih.gov/pubmed/21388963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.231670
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