Bayesian approach for the estimation of cyclosporine area under the curve using limited sampling strategies in pediatric hematopoietic stem cell transplantation

BACKGROUND: The optimal marker for cyclosporine (CsA) monitoring in transplantation patients remains controversial. However, there is a growing interest in the use of the area under the concentration-time curve (AUC), particularly for cyclosporine dose adjustment in pediatric hematopoietic stem cell...

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Dettagli Bibliografici
Pubblicato in:Theor Biol Med Model
Autori principali: Sarem, Sarem, Li, Jun, Barriere, Olivier, Litalien, Catherine, Théorêt, Yves, Lapeyraque, Anne-Laure, Nekka, Fahima
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237955/
https://ncbi.nlm.nih.gov/pubmed/25192585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-11-39
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