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Population pharmacokinetics and Bayesian estimation of tacrolimus exposure in paediatric liver transplant recipients
AIMS: The objectives of this study were to develop a population pharmacokinetic (PopPK) model for tacrolimus in paediatric liver transplant patients and determine optimal sampling strategies to estimate tacrolimus exposure accurately. METHODS: Twelve hour intensive pharmacokinetic profiles from 30 p...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4093930/ https://ncbi.nlm.nih.gov/pubmed/24977292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12276 |
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