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Preclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs
Gene therapy with adeno-associated virus (AAV) has advanced in the last few years from promising results in animal models to >100 clinical trials (reported or under way). While vector availability was a substantial hurdle a decade ago, innovative new production methods now routinely match the sca...
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發表在: | Mol Pain |
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Main Authors: | , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
BioMed Central
2014
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237902/ https://ncbi.nlm.nih.gov/pubmed/25183392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-54 |
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