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Hypomethylation and overexpression of ITGAL (CD11a) in CD4(+) T cells in systemic sclerosis

BACKGROUND: The pathogenesis and etiology of systemic sclerosis (SSc) are complex and poorly understood. To date, several studies have demonstrated that the activation of the immune system undoubtedly plays a pivotal role in SSc pathogenesis. Activated immune effector T cells contribute to the relea...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Wang, YaoYao, Shu, Ye, Xiao, YangFan, Wang, Qing, Kanekura, Takuro, Li, YaPing, Wang, JiuCun, Zhao, Ming, Lu, QianJin, Xiao, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237764/
https://ncbi.nlm.nih.gov/pubmed/25414732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-6-25
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