Down-regulation of MBD4 contributes to hypomethylation and overexpression of CD70 in CD4(+) T cells in systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by lymphocytic infiltration and overproduction of autoantibodies, leading to significant morbidity and mortality. However, the pathogenesis of this disorder has not yet been completely elucidated. It has be...

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Bibliographic Details
Published in:Clin Epigenetics
Main Authors: Liao, Wei, Li, Mengying, Wu, Haijing, Jia, Sujie, Zhang, Nu, Dai, Yong, Zhao, Ming, Lu, Qianjin
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610447/
https://ncbi.nlm.nih.gov/pubmed/29018507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0405-8
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