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Down-regulation of MBD4 contributes to hypomethylation and overexpression of CD70 in CD4(+) T cells in systemic lupus erythematosus
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by lymphocytic infiltration and overproduction of autoantibodies, leading to significant morbidity and mortality. However, the pathogenesis of this disorder has not yet been completely elucidated. It has be...
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| Publicado no: | Clin Epigenetics |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610447/ https://ncbi.nlm.nih.gov/pubmed/29018507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0405-8 |
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