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Hypomethylation Causes MIR21 Overexpression in Tumors
miR-21 is an oncogenic microRNA (miRNA) that is upregulated in many solid tumors. However, the effect of MIR21 hypomethylation on miR-21 expression in tumors and the mechanism of miR-21 DNA demethylation remain unclear. In this study, we confirmed that the expression of miR-21 was significantly incr...
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| Publicado no: | Mol Ther Oncolytics |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7321816/ https://ncbi.nlm.nih.gov/pubmed/32637580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.05.011 |
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