Aurora B Overexpression Causes Aneuploidy and p21(Cip1) Repression during Tumor Development

Aurora kinase B, one of the three members of the mammalian Aurora kinase family, is the catalytic component of the chromosomal passenger complex, an essential regulator of chromosome segregation in mitosis. Aurora B is overexpressed in human tumors although whether this kinase may function as an onc...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: González-Loyola, Alejandra, Fernández-Miranda, Gonzalo, Trakala, Marianna, Partida, David, Samejima, Kumiko, Ogawa, Hiromi, Cañamero, Marta, de Martino, Alba, Martínez-Ramírez, Ángel, de Cárcer, Guillermo, Pérez de Castro, Ignacio, Earnshaw, William C., Malumbres, Marcos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573715/
https://ncbi.nlm.nih.gov/pubmed/26240282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01286-14
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