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Advancing Novel Anesthetics: Pharmacodynamic and Pharmacokinetic Studies of Cyclopropyl-Methoxycarbonyl Metomidate in Dogs

BACKGROUND: Cyclopropyl-methoxycarbonyl metomidate (CPMM, also known as ABP-700) is a second-generation “soft” (i.e., metabolically-labile) etomidate analogue. The purpose of these studies was to characterize CPMM's pharmacology in beagle dogs in preparation for potential first in human phase 1...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Campagna, Jason A., Pojasek, Kevin, Grayzel, David, Randle, John, Raines, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237671/
https://ncbi.nlm.nih.gov/pubmed/25170571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000416
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