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Organocatalysts of oxidative protein folding inspired by protein disulfide isomerase

Organocatalysts derived from diethylenetriamine effect the rapid isomerization of non-native protein disulfide bonds to native ones. These catalysts contain a pendant hydrophobic moiety to encourage interaction with the non-native state, and two thiol groups with low pK(a) values that form a disulfi...

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書目詳細資料
發表在:Org Biomol Chem
Main Authors: Lukesh, John C., Andersen, Kristen A., Wallin, Kelly K., Raines, Ronald T.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237591/
https://ncbi.nlm.nih.gov/pubmed/25266373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01738b
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