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Pyrazine-Derived Disulfide-Reducing Agent for Chemical Biology
For fifty years, dithiothreitol (DTT) has been the preferred reagent for the reduction of disulfide bonds in proteins and other biomolecules. Herein we report on the synthesis and characterization of 2,3-bis(mercaptomethyl)pyrazine (BMMP), a readily accessible disulfide-reducing agent with reactivit...
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| Veröffentlicht in: | Chem Commun (Camb) |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237594/ https://ncbi.nlm.nih.gov/pubmed/25014913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc04491f |
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