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Organocatalysts of oxidative protein folding inspired by protein disulfide isomerase
Organocatalysts derived from diethylenetriamine effect the rapid isomerization of non-native protein disulfide bonds to native ones. These catalysts contain a pendant hydrophobic moiety to encourage interaction with the non-native state, and two thiol groups with low pK(a) values that form a disulfi...
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| Veröffentlicht in: | Org Biomol Chem |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237591/ https://ncbi.nlm.nih.gov/pubmed/25266373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01738b |
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