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Oxidative Protein Folding in vitro: a Study of the Cooperation between Quiescin-sulfhydryl Oxidase and Protein Disulfide Isomerase

The flavin-dependent Quiescin-sulfhydryl oxidase (QSOX) inserts disulfide bridges into unfolded reduced proteins with the reduction of molecular oxygen to form hydrogen peroxide. This work investigates how QSOX and protein disulfide isomerase (PDI) cooperate in vitro to generate native pairings in t...

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Detalhes bibliográficos
Main Authors: Rancy, Pumtiwitt C., Thorpe, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892342/
https://ncbi.nlm.nih.gov/pubmed/18937500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801604x
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