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NLRP3 inflammasome activation by mitochondrial ROS in bronchial epithelial cells is required for allergic inflammation

Abnormality in mitochondria has been suggested to be associated with development of allergic airway disorders. In this study, to evaluate the relationship between mitochondrial reactive oxygen species (ROS) and NLRP3 inflammasome activation in allergic asthma, we used a newly developed mitochondrial...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Kim, S R, Kim, D I, Kim, S H, Lee, H, Lee, K S, Cho, S H, Lee, Y C
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237270/
https://ncbi.nlm.nih.gov/pubmed/25356867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.460
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