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A mitochondrial micropeptide is required for activation of the Nlrp3 Inflammasome

Functional peptides encoded by short open reading frames (sORFs) are emerging as important mediators of fundamental biological processes. Here, we identified a micropeptide produced from a putative long-non-coding RNA that is important in controlling innate immunity. By studying lncRNAs in mice macr...

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Bibliographic Details
Published in:J Immunol
Main Authors: Bhatta, Ankit, Atianand, Maninjay, Jiang, Zhaozhao, Crabtree, Juliet, Blin, Juliana, Fitzgerald, Katherine A.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370245/
https://ncbi.nlm.nih.gov/pubmed/31836654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900791
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