Enrichment of c-Met(+) tumorigenic stromal cells of giant cell tumor of bone and targeting by cabozantinib

Giant cell tumor of bone (GCTB) is a very rare tumor entity, which is little examined owing to the lack of established cell lines and mouse models and the restriction of available primary cell lines. The stromal cells of GCTB have been made responsible for the aggressive growth and metastasis, empha...

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Vydáno v:Cell Death Dis
Hlavní autoři: Liu, L, Aleksandrowicz, E, Fan, P, Schönsiegel, F, Zhang, Y, Sähr, H, Gladkich, J, Mattern, J, Depeweg, D, Lehner, B, Fellenberg, J, Herr, I
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237261/
https://ncbi.nlm.nih.gov/pubmed/25321478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.440
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