Enrichment of c-Met(+) tumorigenic stromal cells of giant cell tumor of bone and targeting by cabozantinib

Giant cell tumor of bone (GCTB) is a very rare tumor entity, which is little examined owing to the lack of established cell lines and mouse models and the restriction of available primary cell lines. The stromal cells of GCTB have been made responsible for the aggressive growth and metastasis, empha...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Liu, L, Aleksandrowicz, E, Fan, P, Schönsiegel, F, Zhang, Y, Sähr, H, Gladkich, J, Mattern, J, Depeweg, D, Lehner, B, Fellenberg, J, Herr, I
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237261/
https://ncbi.nlm.nih.gov/pubmed/25321478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.440
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