Delivery of improved oncolytic adenoviruses by mesenchymal stromal cells for elimination of tumorigenic pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive malignancies and has poor therapeutic options. We evaluated improved oncolytic adenoviruses (OAds), in which the adenoviral gene E1B19K was deleted or a TRAIL transgene was inserted. Bone marrow mesenchymal stromal cells (MSCs) ser...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Kaczorowski, Adam, Hammer, Katharina, Liu, Li, Villhauer, Sabine, Nwaeburu, Clifford, Fan, Pei, Zhao, Zhefu, Gladkich, Jury, Groß, Wolfgang, Nettelbeck, Dirk M., Herr, Ingrid
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891025/
https://ncbi.nlm.nih.gov/pubmed/26824985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7031
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