Delivery of improved oncolytic adenoviruses by mesenchymal stromal cells for elimination of tumorigenic pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive malignancies and has poor therapeutic options. We evaluated improved oncolytic adenoviruses (OAds), in which the adenoviral gene E1B19K was deleted or a TRAIL transgene was inserted. Bone marrow mesenchymal stromal cells (MSCs) ser...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kaczorowski, Adam, Hammer, Katharina, Liu, Li, Villhauer, Sabine, Nwaeburu, Clifford, Fan, Pei, Zhao, Zhefu, Gladkich, Jury, Groß, Wolfgang, Nettelbeck, Dirk M., Herr, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891025/
https://ncbi.nlm.nih.gov/pubmed/26824985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7031
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