Wird geladen...
The mechanisms behind the therapeutic activity of BET bromodomain inhibition
The bromodomain and extra-terminal (BET) protein Brd4 recruits transcriptional regulatory complexes to acetylated chromatin. While Brd4 is considered to be a general transcriptional regulator, pharmacological inhibition of BET proteins shows therapeutic activity in a variety of different pathologies...
Gespeichert in:
| Veröffentlicht in: | Mol Cell |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236231/ https://ncbi.nlm.nih.gov/pubmed/24905006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.05.016 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|