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Activating Human Genes with Zinc Finger Proteins, TALEs, and CRISPR/Cas9 for Gene Therapy and Regenerative Medicine

New technologies have recently been developed to control the expression of human genes in their native genomic context by engineering synthetic transcription factors that can be targeted to any DNA sequence. The ability to precisely regulate any gene as it occurs naturally in the genome provides a m...

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Bibliografiske detaljer
Udgivet i:Expert Opin Ther Targets
Main Authors: Gersbach, Charles A., Perez-Pinera, Pablo
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236187/
https://ncbi.nlm.nih.gov/pubmed/24917359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2014.913572
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