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Activating Human Genes with Zinc Finger Proteins, TALEs, and CRISPR/Cas9 for Gene Therapy and Regenerative Medicine

New technologies have recently been developed to control the expression of human genes in their native genomic context by engineering synthetic transcription factors that can be targeted to any DNA sequence. The ability to precisely regulate any gene as it occurs naturally in the genome provides a m...

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Detalles Bibliográficos
Publicado en:Expert Opin Ther Targets
Autores principales: Gersbach, Charles A., Perez-Pinera, Pablo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236187/
https://ncbi.nlm.nih.gov/pubmed/24917359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2014.913572
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