QseC Inhibitors as an Antivirulence Approach for Gram-Negative Pathogens

Invasive pathogens interface with the host and its resident microbiota through interkingdom signaling. The bacterial receptor QseC, which is a membrane-bound histidine sensor kinase, responds to the host stress hormones epinephrine and norepinephrine and the bacterial signal AI-3, integrating interk...

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Pubblicato in:mBio
Autori principali: Curtis, Meredith M., Russell, Regan, Moreira, Cristiano G., Adebesin, Adeniyi M., Wang, Changguang, Williams, Noelle S., Taussig, Ron, Stewart, Don, Zimmern, Philippe, Lu, Biao, Prasad, Ravi N., Zhu, Chen, Rasko, David A., Huntley, Jason F., Falck, John R., Sperandio, Vanessa
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235214/
https://ncbi.nlm.nih.gov/pubmed/25389178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02165-14
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