QseC inhibition as an antivirulence approach for colitis-associated bacteria

Hosts and their microbes have established a sophisticated communication system over many millennia. Within mammalian hosts, this dynamic cross-talk is essential for maintaining intestinal homeostasis. In a genetically susceptible host, dysbiosis of the gut microbiome and dysregulated immune response...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rooks, Michelle G., Veiga, Patrick, Reeves, Analise Z., Lavoie, Sydney, Yasuda, Koji, Asano, Yasunari, Yoshihara, Kazufumi, Michaud, Monia, Wardwell-Scott, Leslie, Gallini, Carey Ann, Glickman, Jonathan N., Sudo, Nobuyuki, Huttenhower, Curtis, Lesser, Cammie F., Garrett, Wendy S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224399/
https://ncbi.nlm.nih.gov/pubmed/27980034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612836114
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