Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE).

We have evaluated the subunit composition of plasma von Willebrand factor (vWF) and found evidence that cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease (vWD), but decreased or absent in variants with aberrant structure of individual oligomers. vWF was rapid...

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Détails bibliographiques
Auteurs principaux: Zimmerman, T S, Dent, J A, Ruggeri, Z M, Nannini, L H
Format: Artigo
Langue:Inglês
Publié: 1986
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC423489/
https://ncbi.nlm.nih.gov/pubmed/3485111
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