Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE).

We have evaluated the subunit composition of plasma von Willebrand factor (vWF) and found evidence that cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease (vWD), but decreased or absent in variants with aberrant structure of individual oligomers. vWF was rapid...

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Pubblicato in:	J Clin Invest
Autori principali:	Zimmerman, T S, Dent, J A, Ruggeri, Z M, Nannini, L H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423489/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3485111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112394
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