Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE).

We have evaluated the subunit composition of plasma von Willebrand factor (vWF) and found evidence that cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease (vWD), but decreased or absent in variants with aberrant structure of individual oligomers. vWF was rapid...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Zimmerman, T S, Dent, J A, Ruggeri, Z M, Nannini, L H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423489/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3485111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112394
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