Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE).

Ítems similars

• Aberrant multimeric structure of von Willebrand factor in a new variant of von Willebrand's disease (type IIC).
  per: Ruggeri, Z M, et al.
  Publicat: (1982)
• von Willebrand factor interaction with the glycoprotein IIb/IIa complex. Its role in platelet function as demonstrated in patients with congenital afibrinogenemia.
  per: De Marco, L, et al.
  Publicat: (1986)
• Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.
  per: Dent, J A, et al.
  Publicat: (1990)
• Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin.
  per: Berkowitz, S D, et al.
  Publicat: (1987)
• von Willebrand factor binds to platelets and induces aggregation in platelet-type but not type IIB von Willebrand disease.
  per: Miller, J L, et al.
  Publicat: (1983)