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In vitro correction of the abnormal multimeric structure of von Willebrand factor in type IIa von Willebrand's disease.

Type IIa von Willebrand's disease (vWd) has been characterized by the absence of the largest and a reduction in the intermediate-sized multimers of the plasma and platelet von Willebrand factor (vWf) and by the diminished response of the platelet-rich plasma of these patients to ristocetin. Other re...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gralnick, H R, Williams, S B, McKeown, L P, Maisonneuve, P, Jenneau, C, Sultan, Y, Rick, M E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390675/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2994057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.17.5968
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