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Differential Stimulation of Insulin Secretion by GLP-1 and Kisspeptin-10

β-cells in the pancreatic islet respond to elevated plasma glucose by secreting insulin to maintain glucose homeostasis. In addition to glucose stimulation, insulin secretion is modulated by numerous G-protein coupled receptors (GPCRs). The GPCR ligands Kisspeptin-10 (KP) and glucagon-like peptide-1...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Schwetz, Tara A., Reissaus, Christopher A., Piston, David W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234631/
https://ncbi.nlm.nih.gov/pubmed/25401335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113020
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