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Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms
Pancreatic β-cells regulate glucose homeostasis by secreting insulin in response to glucose elevation and G protein-coupled receptor (GPCR) activation. Neuropeptide Y (NPY) and somatostatin (SST) attenuate insulin secretion through G(i) activation of Y(1) and SSTR(1&5) receptors, respectively. T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543566/ https://ncbi.nlm.nih.gov/pubmed/23211512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00374.2012 |
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