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Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms

Pancreatic β-cells regulate glucose homeostasis by secreting insulin in response to glucose elevation and G protein-coupled receptor (GPCR) activation. Neuropeptide Y (NPY) and somatostatin (SST) attenuate insulin secretion through G(i) activation of Y(1) and SSTR(1&5) receptors, respectively. T...

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書誌詳細
主要な著者: Schwetz, Tara A., Ustione, Alessandro, Piston, David W.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543566/
https://ncbi.nlm.nih.gov/pubmed/23211512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00374.2012
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