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Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney
Inflammation is accompanied by the release of highly reactive oxygen and nitrogen species (RONS) that damage DNA, among other cellular molecules. Base excision repair (BER) is initiated by DNA glycosylases and is crucial in repairing RONS-induced DNA damage; the alkyladenine DNA glycosylase (Aag/Mpg...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4234618/ https://ncbi.nlm.nih.gov/pubmed/25349415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413582111 |
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