A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver

Hepatic metabolism requires mitochondria to adapt their bioenergetic and biosynthetic output to accompany the ever-changing anabolic/catabolic state of the liver cell, but the wiring of this process is still largely unknown. Using a postprandial mouse liver model and quantitative cryo-EM analysis, w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sood, Aditi, Jeyaraju, Danny Vijey, Prudent, Julien, Caron, Alexandre, Lemieux, Philippe, McBride, Heidi May, Laplante, Mathieu, Tóth, Katalin, Pellegrini, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234614/
https://ncbi.nlm.nih.gov/pubmed/25352671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408061111
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