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OPA1 requires mitofusin 1 to promote mitochondrial fusion

The regulated equilibrium between mitochondrial fusion and fission is essential to maintain integrity of the organelle. Mechanisms of mitochondrial fusion are largely uncharacterized in mammalian cells. It is unclear whether OPA1, a dynamin-related protein of the inner membrane mutated in autosomal...

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Bibliografiske detaljer
Main Authors: Cipolat, Sara, de Brito, Olga Martins, Dal Zilio, Barbara, Scorrano, Luca
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC528769/
https://ncbi.nlm.nih.gov/pubmed/15509649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407043101
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