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OPA1 requires mitofusin 1 to promote mitochondrial fusion

The regulated equilibrium between mitochondrial fusion and fission is essential to maintain integrity of the organelle. Mechanisms of mitochondrial fusion are largely uncharacterized in mammalian cells. It is unclear whether OPA1, a dynamin-related protein of the inner membrane mutated in autosomal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cipolat, Sara, de Brito, Olga Martins, Dal Zilio, Barbara, Scorrano, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC528769/
https://ncbi.nlm.nih.gov/pubmed/15509649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407043101
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