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The mechanism of Torsin ATPase activation

Torsins are membrane-associated ATPases whose activity is dependent on two activating cofactors, lamina-associated polypeptide 1 (LAP1) and luminal domain-like LAP1 (LULL1). The mechanism by which these cofactors regulate Torsin activity has so far remained elusive. In this study, we identify a cons...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Brown, Rebecca S. H., Zhao, Chenguang, Chase, Anna R., Wang, Jimin, Schlieker, Christian
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234599/
https://ncbi.nlm.nih.gov/pubmed/25352667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415271111
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