Human NLRP3 inflammasome senses multiple types of bacterial RNAs

Inflammasomes are multiprotein platforms that activate caspase-1, which leads to the processing and secretion of the proinflammatory cytokines IL-1β and IL-18. Previous studies demonstrated that bacterial RNAs activate the nucleotide-binding domain, leucine-rich-repeat-containing family, pyrin domai...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Sha, Wenwen, Mitoma, Hiroki, Hanabuchi, Shino, Bao, Musheng, Weng, Leiyun, Sugimoto, Naoshi, Liu, Ying, Zhang, Zhiqiang, Zhong, Jin, Sun, Bing, Liu, Yong-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234566/
https://ncbi.nlm.nih.gov/pubmed/25355909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412487111
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