Orally Bioavailable 6-Chloro-7-methoxy-4(1H)-quinolones Efficacious against Multiple Stages of Plasmodium

[Image: see text] The continued proliferation of malaria throughout temperate and tropical regions of the world has promoted a push for more efficacious treatments to combat the disease. Unfortunately, more recent remedies such as artemisinin combination therapies have been rendered less effective d...

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Bibliographic Details
Published in:J Med Chem
Main Authors: Cross, R. Matthew, Flanigan, David L., Monastyrskyi, Andrii, LaCrue, Alexis N., Sáenz, Fabián E., Maignan, Jordany R., Mutka, Tina S., White, Karen L., Shackleford, David M., Bathurst, Ian, Fronczek, Frank R, Wojtas, Lukasz, Guida, Wayne C., Charman, Susan A., Burrows, Jeremy N., Kyle, Dennis E., Manetsch, Roman
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234439/
https://ncbi.nlm.nih.gov/pubmed/25148516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500942v
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