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Expression, purification and characterization of soluble red rooster laforin as a fusion protein in Escherichia coli
BACKGROUND: The gene that encodes laforin, a dual-specificity phosphatase with a carbohydrate-binding module, is mutated in Lafora disease (LD). LD is an autosomal recessive, fatal progressive myoclonus epilepsy characterized by the intracellular buildup of insoluble, hyperphosphorylated glycogen-li...
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| Publicado no: | BMC Biochem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4234410/ https://ncbi.nlm.nih.gov/pubmed/24690255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-15-8 |
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