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Asialo von Willebrand factor interactions with platelets. Interdependence of glycoproteins Ib and IIb/IIIa for binding and aggregation.

Asialo von Willebrand factor (AS-vWf) binds to and aggregates normal human platelets in the absence of ristocetin. Maximal specific binding of AS-vWf is 1-2 micrograms vWf protein/10(8) platelets. Despite the specificity of the binding, only 60% of the bound AS-vWf can be dissociated after equilibri...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Grainick, H R, Williams, S B, Coller, B S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423389/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2981249/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111673
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