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Synthesis and Biological Evaluation of Sophoridinol Derivatives as a Novel Family of Potential Anticancer Agents
[Image: see text] New N-substituted sophoridinic acid/ester and sophoridinol derivatives were synthesized and evaluated for their cytotoxic activity in human HepG2 hepatoma cells from the lead sophoridine (1). Among the newly synthesized compounds, sophoridinol 7i displayed a potential antiprolifera...
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| Udgivet i: | ACS Med Chem Lett |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233360/ https://ncbi.nlm.nih.gov/pubmed/25408835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500289h |
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