Structure–Metabolism Relationships in the Glucuronidation of d-Amino Acid Oxidase Inhibitors

[Image: see text] Representative d-amino acid oxidase (DAAO) inhibitors were subjected to in vitro liver microsomal stability tests in the absence or presence of uridine diphosphate glucuronic acid (UDPGA). While carboxylate-based DAAO inhibitors displayed little glucuronidation, most DAAO inhibitor...

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Bibliografiska uppgifter
I publikationen:ACS Med Chem Lett
Huvudupphovsmän: Zimmermann, Sarah C., Rais, Rana, Alt, Jesse, Burzynski, Caitlin, Slusher, Barbara S., Tsukamoto, Takashi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2014
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233358/
https://ncbi.nlm.nih.gov/pubmed/25408840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500335z
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