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Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase
A series of kojic acid (5-hydroxy-2-hydroxymethyl-4H-pyran-4-one) derivatives were synthesized and tested for their ability to inhibit D-amino acid oxidase (DAAO). Various substituents were incorporated into kojic acid at its 2-hydroxymethyl group. These analogs serve as useful molecular probes to e...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678123/ https://ncbi.nlm.nih.gov/pubmed/23683589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.04.062 |
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