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Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes
Eukaryotic RNAs with premature termination codons (PTCs) are eliminated by nonsense-mediated decay (NMD). While human nonsense RNA degradation can be initiated either by an endonucleolytic cleavage event near the PTC or through decapping, the individual contribution of these activities on endogenous...
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| 出版年: | Genes Dev |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233243/ https://ncbi.nlm.nih.gov/pubmed/25403180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.246538.114 |
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