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Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances

While global chromatin conformation studies are emerging, very little is known about the chromatin conformation of human telomeres. Most studies have focused on the role of telomeres as a tumor suppressor mechanism. Here we describe how telomere length regulates gene expression long before telomeres...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Robin, Jérôme D., Ludlow, Andrew T., Batten, Kimberly, Magdinier, Frédérique, Stadler, Guido, Wagner, Kathyrin R., Shay, Jerry W., Wright, Woodring E.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233240/
https://ncbi.nlm.nih.gov/pubmed/25403178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.251041.114
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