Lethal impairment of cholinergic neurotransmission in hemicholinium-3-sensitive choline transporter knockout mice

Presynaptic acetylcholine (ACh) synthesis and release is thought to be sustained by a hemicholinium-3-sensitive choline transporter (CHT). We disrupted the murine CHT gene and examined CHT–/– and +/– animals for evidence of impaired cholinergic neurotransmission. Although morphologically normal at b...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Ferguson, Shawn M., Bazalakova, Mihaela, Savchenko, Valentina, Tapia, Juan Carlos, Wright, Jane, Blakely, Randy D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2004
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423269/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15173594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401667101
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk