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Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix
MspJI belongs to a family of restriction enzymes that cleave DNA containing 5-methylcytosine (5mC) or 5-hydroxymethylcytosine (5hmC). MspJI is specific for the sequence 5(h)mC-N-N-G or A and cleaves with some variability 9/13 nucleotides downstream. Earlier, we reported the crystal structure of MspJ...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231741/ https://ncbi.nlm.nih.gov/pubmed/25262349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku871 |
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