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Chemical Display of Pyrimidine Bases Flipped Out by Modification-Dependent Restriction Endonucleases of MspJI and PvuRts1I Families

The epigenetic DNA modifications 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) in eukaryotes are recognized either in the context of double-stranded DNA (e.g., by the methyl-CpG binding domain of MeCP2), or in the flipped-out state (e.g., by the SRA domain of UHRF1). The SRA-like domains...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Zagorskaitė, Evelina, Sasnauskas, Giedrius
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259335/
https://ncbi.nlm.nih.gov/pubmed/25486533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114580
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