Catabolism of (2E)-4-Hydroxy-2-nonenal via ω- and ω-1-Oxidation Stimulated by Ketogenic Diet

Oxidative stress triggers the peroxidation of ω-6-polyunsaturated fatty acids to reactive lipid fragments, including (2E)-4-hydroxy-2-nonenal (HNE). We previously reported two parallel catabolic pathways of HNE. In this study, we report a novel metabolite that accumulates in rat liver perfused with...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Jin, Zhicheng, Berthiaume, Jessica M., Li, Qingling, Henry, Fabrice, Huang, Zhong, Sadhukhan, Sushabhan, Gao, Peng, Tochtrop, Gregory P., Puchowicz, Michelle A., Zhang, Guo-Fang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231705/
https://ncbi.nlm.nih.gov/pubmed/25274632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602458
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